Aylar: Mart 2024

Over the past 50 years, our understanding of cancer has evolved from its viral origin to a complex systemic disease. Along the way, improved diagnosis and therapeutics saved millions of lives. To mark Cell’s 50th anniversary, this focus issue envisions

In less than a decade, Ireland has seen many previously unimaginable developments, including the legalisation of same-sex marriage, the radical overhaul of the country’s archaic abortion law, and the beginnings of implementation of an ambitious plan to create a universally

Two weeks ago, the Guardian reported that in 2019, Frank Hester, chief executive of the Phoenix Partnership, and the conservative party’s biggest donor, said that: “It’s like trying not to be racist but you see Diane Abbott on TV, and

bmj;384/mar27_16/q733/FAF1faPaul Wallace, emeritus David Cohen professor of primary healthcare, University College London (UCL), had a mantra: “GPs are experts in normality.” Unlike many hospital specialists, he explained, GPs were less prone to over-investigate and go down rabbit holes leading nowhere.

Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.

The association between consumption of ultra-processed food and adverse health outcomes seems to be established.1 As with most observational epidemiology, however, the key question is whether this reflects a causal relation. To do this, we need to go beyond ever

The diagnostics company Randox Health has removed advertisements for its type 1 diabetes genetic test after receiving complaints that it was using fear and stoking anxiety to push its product.The adverts, displayed in London Underground stations, referred to type 1

Earlier this month, I was among the first cohort of medical students to be assigned their foundation training post by the preference informed allocation system, which gives each applicant a random, computer generated ranking.1 Although the UK Foundation Programme Office

The past 5 years in Europe have been characterised by crisis. Long-standing Euroscepticism culminated in the UK’s exit of the EU in 2020. Europe was unprepared for the COVID-19 pandemic, which pushed even the best health systems to their limits,

This is the chest radiograph of a woman in her late 80s with a history of hypertension, diabetes, heart failure, and atrial fibrillation (fig 1). She had been referred because of fever and worsening dyspnoea. Examination showed bilateral lung crackles,

bmj;384/mar20_15/q702/FAF1faIvor Browne, professor emeritus of psychiatry at University College Dublin, was best known for his theory that trauma is at the root of many psychiatric diagnoses. He transformed the public perception of mental illness in Ireland and oversaw the move

After the initial randomized clinical trials and emergency use authorization of the COVID-19 vaccines by the US Food and Drug Administration (FDA) during the COVID-19 pandemic, the US Centers for Disease Control and Prevention (CDC) and the FDA undertook extensive

Healthcare in the UK is facing a crisis. At issue is the creation of new groups of health workers called physician associates (PAs) and anaesthetic associates (AAs).1 Originally PAs and AAs were envisaged as assistants to doctors to increase their

The BMA has urged the government to launch an independent inquiry into hospitals’ use of physician associates (PAs) to replace doctors on medical rotas. The association has asked the health and social care secretary, Victoria Atkins. to examine how widespread

AbstractObjectivesTo assess the rates of SARS-CoV-2 positivity in babies born to mothers with SARS-CoV-2 infection, the timing of mother-to-child transmission and perinatal outcomes, and factors associated with SARS-CoV-2 status in offspring.DesignLiving systematic review and meta-analysis.Data sourcesMajor databases between 1 December

Cell expands its formats to include the Short Article and explains why.

On March 5, Super Tuesday, 16 states and one territory held primary elections to nominate candidates for the 2024 presidential race. As expected, the results confirmed that President Joe Biden will again compete with former President Donald Trump for the

bmj;384/mar13_13/q635/FAF1faWhen paediatrician Colin Walker began his career, the care of frail newborns consisted of little more than keeping them warm and offering fluids. Walker, who has died aged 100, was instrumental in a huge sea change in neonatal care. He

In this issue of JAMA, a study by Harlow and colleagues found that 11% of US high school seniors (ie, 12th grade) reported using Δ8-tetrahdyrocannabinol (Δ8-THC) in the past 12 months based on a 2023 survey. This study is a

A seminal moment beckons in the history of the Royal College of Physicians (RCP). Tomorrow the RCP is due to hold an extraordinary general meeting (EGM)—notably only the third EGM in its 505 year history. The centre of debate? Physician

President Joe Biden vowed to safeguard reproductive rights and restore Roe v Wade as “the law of the land” in his final state of the union speech before the US election.In his speech to members of the House of Representatives

The International AIDS Society (IAS) and UNAIDS have spoken out against legislation passed by Ghana’s parliament last week that would impose prison sentences of up to three years on anyone who identifies as gay, and up to five years on

For most women, menopause is a natural phase of life that they transition as part of biological ageing. However, as highlighted in a Series of four papers in today’s Lancet—published ahead of International Women’s Day on March 8—commercial companies and

How do we model our lives from the time of a major diagnosis to death? Illness trajectories are one method, and they can help frame a conversation about what life will be like with a progressive illness. The three characteristic

Resistance to the first line HIV antiretroviral drug dolutegravir is growing and exceeding levels seen in clinical trials, the World Health Organization has warned.1Surveys conducted in Malawi, Uganda, and Ukraine found that levels of resistance among those receiving dolutegravir based

Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.

The steep decline in children’s health under the current government’s watch is a national scandal, documented in the Academy of Medical Sciences scathing report.1 Levels of destitution not seen since the earlier 20th century are just the tip of an

Numerous studies have identified fine particulate matter (PM)2.5, a critical component of air pollution, as a risk factor for cardiovascular disease.1 In a notable update in 2021—the first since 2005—the World Health Organization tightened its air quality guidelines for PM2.5.23

The Intergovernmental Negotiating Body (INB), which is tasked under WHO with drawing up an international instrument on pandemic prevention, preparedness, and response, will sit for the 9th and final time from March 18–29. In the 2 years since it first

In Nigeria, the rapidly escalating drug prices are indicative of a deeper issue: fundamentally, it’s about the economy. The situation shows no signs of abating, especially as recent reports in January 2024 indicated inflation has surged to a 27 year

Some of the most significant discoveries in the life sciences over the last 50 years stem from genetics and genomics. This field has also seen large-scale collaborative efforts yield fundamental milestones and results, such as the Human Genome Project. Despite