Psikiyatri

Categories allow us to create order, altering the way we are able to act and interact, but they are also by nature constraining, creating divisions that must be agreed to track reality in order to be useful. Work in early

World Psychiatry, Volume 22, Issue 3, Page 413-414, October 2023.

Depression and dementia can lead to generalised cognitive and memory dysfunction. Thus, differentiating these disorders is important and challenging. Pseudodementia is a term used clinically to describe symptoms that resemble dementia but are caused by other conditions (most frequently depression),

China’s rapidly growing economy and urbanisation have lifted much of its population out of poverty, but have also created new psychological pressures. With the world’s second largest population, at over 1·4 billion, even minor shifts in the prevalence of mental

Background Many people who are gender variant have undiagnosed gender dysphoria, resulting in delayed receipt of gender-affirming support and prolonged distress in living with their gender-non-conforming sex. The Utrecht Gender Dysphoria Scale-Gender Spectrum (UGDS-GS) is a newly developed tool that

Substance use is responsible for 5·5% of the global burden of disease. The prevalence of alcohol and drug use disorders is rising globally but shows considerable regional variation. Public health measures, such as public consumption bans and minimum legal age,

Research in psychiatry seeks causes, to understand what makes a disorder or symptom begin or change. Causal inferences require cutting out the noise from the complexity of unique individuals with subjective experiences in particular circumstances so that a signal appears.

Somatic symptom disorder (SSD) is a new diagnosis introduced into the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which is expected to solve the diagnostic difficulties of patients with medically unexplained symptoms. Based on the previous work,

Background The association between antipsychotics and cardiovascular diseases (CVDs) remains significant yet unestablished, especially in Chinese populations. Objective To investigate the risk of CVDs associated with antipsychotics among Chinese individuals with schizophrenia. Methods We conducted a nested case–control study on

Background In the recent digital era, individuals with internet gaming disorder (IGD) have reported a much higher prevalence of poor sleep quality, perceived stress and suicidal behaviour. However, the underlying mechanisms for these psychological problems remain unknown. Aims The primary

Background Cognitive–behavioural therapy for insomnia (CBTi) is the first-line treatment for those with this sleep disorder. However, depressive and anxiety symptoms often co-occur with acute insomnia, which may affect the effectiveness of CBTi treatment. Aims This study aimed to determine

Mental disorders are now recognised as some of the leading causes of disease burden globally but, to appreciate their full impact on individuals and societies, we must consider their role in early mortality. Although statistics consistently show a large difference

World Psychiatry, Volume 22, Issue 2, Page 325-326, June 2023.

World Psychiatry, Volume 22, Issue 1, Page 42-43, February 2023.

Mental health care in Ukraine was already undergoing reorganisation before the second Russian invasion on Feb 24, 2022. The country had inherited Soviet-style health care when it became independent in 1991. This comprised a large, institutionalised psychiatric system associated with

Mental health disorders can be understood on various levels, from the phenomenological to the neurobiological. In parallel, they are considered to arise through a wide range of influences, from a person’s social environment to their genetics and neurodevelopment. Integrating these

Nicotine use is more prevalent in patients with psychiatric disorders, especially those diagnosed with psychotic illnesses. Previously, this higher prevalence has been partially attributed to the potential ameliorative effects of nicotine on symptom severity and cognitive impairment. Some healthcare professionals

Although logistic regression is the most popular for modelling regression relationships with binary responses, many find relative risk (RR), or risk ratio, easier to interpret and prefer to use this measure of risk in regression analysis. Indeed, since Zou published

In December 2022, New York City Mayor Eric Adams announced he would be directing police and emergency responders throughout the city to bring people living on the streets, and with apparent mental illness, and unable to meet their basic needs,

Objective Umbrella reviews are a new form of literature review that summarises the strength and/or quality of the evidence from all systematic reviews and meta-analyses conducted on a broad topic. This type of review thus provides an exhaustive examination of

Question Are antipsychotic dose equivalents between acute mania and schizophrenia the same? Study selection and analysis Six databases were systematically searched (from inception to 17 September 2022) to identify blinded randomised controlled trials (RCTs) that used a flexible-dose oral antipsychotic

Background Early screening of cognitive function is critical to dementia treatment and care. However, traditional tests require face-to-face administration and are often limited by implementation costs and biases. Aims This study aimed to assess whether the Thoven Cognitive Self-Assessment (TCSA),

Objectives The WHO’s Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) has been widely used in low and middle-income countries. We reviewed literature describing interventions and training programmes beyond the mhGAP-IG, in primary healthcare (PHC) and community-based healthcare (CBH). Design

Individual rights are integral to modern psychiatry but articulating these rights, particularly in legislation, is challenging and can be controversial. While the right to life is regarded as fundamental, does this apply to the right to end one’s own life?

Background Advancements in research have confirmed that gut microbiota can influence health through the microbiota–gut–brain axis. Meditation, as an inner mental exercise, can positively impact the regulation of an individual’s physical and mental health. However, few studies have comprehensively investigated

World Psychiatry, Volume 22, Issue 1, Page 46-47, February 2023.

Background Depression, one of the most frequent complications after stroke, increases the disease’s burden and physical disability. Poststroke depression (PSD) is a multifactorial disease with genetic, environmental and biological factors involved in its occurrence. Genetic studies on PSD to date

Objectives The WHO’s Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) has been widely used in low and middle-income countries. We reviewed literature describing interventions and training programmes beyond the mhGAP-IG, in primary healthcare (PHC) and community-based healthcare (CBH). Design

Background The conclusion that people with severe mental illness require involuntary care to protect their health (including threats due to physical—non-psychiatric—illness) is challenged by findings indicating that they often lack access to general healthcare and the assertion that they would

Disturbances of mind have in some times and places been seen as intrinsically connected to the body. The holistic approaches of ancient Chinese and Ayurvedic medicine focus on this interconnection and the need for balance, as did the Hippocratic medicine

The end of a year provides a convenient marker for reflection; a time to look back at accomplishments and failures. Simply evaluating the past 12 months would be trivial without also looking forward, using recent experience to determine what lies

Wealthy nations must step up support for Africa and vulnerable countries in addressing past, present and future impacts of climate change The 2022 report of the Intergovernmental Panel on Climate Change paints a dark picture of the future of life

Everyone is different but, to paraphrase George Orwell, some are more different than others. While physical differences are more noticeable, emotional, cognitive, and behavioural differences can be more profound—they make us who we are. Society has gradually become more accepting

Background Major depressive disorder (MDD) is a common psychiatric disease and a leading cause of disability worldwide. Handgrip strength (HGS) as an objective physical fitness test is a practical index for identifying many diseases. Previous studies drew different conclusions about

World Psychiatry, Volume 21, Issue 3, Page 461-462, October 2022.

For much of the 20th century, the male arena of war was the focus for understanding traumatic experiences. Late-19th-century psychiatry had included the sphere of the family and childhood sexual abuse, but they were largely left aside until the 1980s.

Background The management of modifiable risk factors and comorbidities may impact the future trajectory of cognitive impairment, but easy-to-implement management methods are lacking. Aims This study investigated the effects of simple but comprehensive cognitive health management practices on the cognitive

Background Mental health problems are prevalent among patients seeking primary healthcare. However, traditional patient interviews often fail to identify and manage these problems. Therefore, an improved patient interview process is needed to assess and treat mental health problems in primary

In this issue of The Lancet Psychiatry, Joseph F Hayes and colleagues present new findings on the temporal dynamics of severe mental illness diagnoses and physical health comorbidities. Although the wide gap in physical health and lifespan between those with

Bipolar depression (BD-D) is both common and incredibly challenging to treat. Even treated individuals with BD-D experience depression approximately 19% of the time, and subsyndromal depression an additional 18%. This stands in clear contrast to the approximately 10% of time

Improving child and adolescent mental health requires the careful development and rigorous testing of interventions and delivery methods. This includes universal school-based mindfulness training, evaluated in the My Resilience in Adolescence (MYRIAD) trial reported in this special edition. While discovering

The metaverse and non-fungible tokens (NFTs) were some of the hottest tech terms in 2021, according to a Google Trends search. Our review aims to describe the metaverse and NFTs in the context of their potential application in the treatment

Attributed to the Dutch humanist scholar, Desiderius Erasmus, the concept of proactive awareness and preventative interventions being more effective than later remedial action has never been more relevant in mental health. Initiatives such as the WHO Mental Health Gap Action

A seizure is one of the most uncommon severe adverse side effects of antipsychotics. Clinical recognition rates for it are low, especially for psychomotor seizures. The authors present a case of psychomotor seizure caused by amisulpride to treat schizophrenia. A

Background Parkinson’s disease (PD) is associated with perceived stigma and affects quality of life (QoL). Additional health conditions may influence these consequences of PD. Aims This study assessed the impact of health conditions on perceived stigma and QoL in persons

Some messages have to be repeated again and again, especially when they are calling for a meaningful shift in view. As Thomas Kuhn argued in 1962, when problems arise in an explanatory framework or system, they initially pass beneath our

Background Self-reflectiveness, one dimension of cognitive insight, plays a protective role in an individual’s mental state. Both high and low levels of self-reflectiveness have been reported in patients with schizophrenia and individuals at clinical high risk for the illness. Aims

Suppose we have a sample of subjects in two treatment groups. To study the difference of the treatment effects, we can analyse the data using all subjects (overall analysis). We may also divide the subjects into several subgroups based on

In this issue, a Commission on intimate partner violence and mental health, led by Sian Oram, Helen Fisher, and Louise Howard, summarises current knowledge on this crucial topic and lays out a roadmap of recommendations to reduce incidence and aid

World Psychiatry, Volume 21, Issue 2, Page 217-218, June 2022.

In 2019, the Topol review was published on behalf of the secretary of state for health and social care in the UK, preparing the healthcare workforce to deliver the digital future.1 A multidisciplinary team of experts, including clinicians, researchers, ethicists,

Politicians and military leaders might be able to think in terms of gains and victories, but for the civilians, and many of the ordinary soldiers, involved, there are only losses: loss of home, family, friends, employment, education, as well as

Background The ongoing pandemic has led to a global surge in coronavirus disease 2019 (COVID-19)-related mental health research. However, most related publications come from Western countries or China, and their findings cannot always be extrapolated to Arab countries. Aims This

Psychiatry has an ugly history concerning sexual orientation and gender, having previously pathologised those attracted to the same sex or who did not conform to feminine or masculine norms. After late-19th century psychiatrists attempted to explain what they saw as

Background The importance of psychosocial functioning in the assessment, diagnosis and treatment of major depressive disorder (MDD) is widely recognised. However, there is a lack of effective scales to assess psychosocial functioning in patients with MDD. Aims To develop a

At the stroke of midnight on Jan 1, 2022, tens of millions of Americans started their new year by watching the ball drop in New York City’s Times Square, a tradition dating back to 1908. After 2 years of the

Background Childhood trauma (CT) is an important risk factor in the emergence and clinical course of psychiatric disorders. In the latest literature, an association exists between CT and patients with schizophrenia. There is also a strong relationship between the dissociative

Societies may be judged by how well they care for those who are most at risk, particularly those who are least able to speak up for themselves, such as people with mental disorders. Vulnerable groups have been particularly adversely affected

Objective The current practice in meta-analysis of the effects of psychopharmacological interventions ignors the administered dose or restricts the analysis in a dose range. This may introduce unnecessary uncertainty and heterogeneity. Methods have been developed to integrate the dose–effect models

World Psychiatry, Volume 21, Issue 1, Page 56-57, February 2022.

Arachnoid cysts have been linked to neuropsychiatric morbidity. We describe two patients presenting with dissociative and manic symptoms believed to be associated with middle fossa arachnoid cysts. They were managed medically and remitted eventually, but symptoms were resistant. We briefly

The COVID-19 pandemic brought with it some predictable consequences for research: labs and universities across the globe were forced to shut their doors; large-scale collaborations ground to a halt; and many clinical trials were stopped or significantly curtailed. Mental health

Background Although the link between gut microbiota and depression has been suggested, changes of gut microbiota vary largely among individuals with depression. Aims Explore the heterogeneity of microbiota–gut–brain axis and new pathogenic characteristics in murine models of depression. Methods Adolescent

Background Developing accurate identification methods for individuals with suicide attempts and providing them with follow-up care and supports can be a vital component of all comprehensive suicide prevention strategies. However, because of the difficulties concerning one’s intentions behind injurious behaviour,

Background Obsessive-compulsive disorder (OCD) is considered a very debilitating disorder with severe loss of quality of life and income. Aims This study estimates the quality of life and economic consequences of OCD in China. Methods The research team interviewed 639

Background The corpus callosum (CC) is the most targeted region in the cerebrum that integrates cognitive data between homologous areas in the right and left hemispheres. Aims Our study used statistical analysis to determine whether there was a correlation between

Women who experience abrupt onset of affective and psychotic symptoms within 2 weeks of childbirth are considered to have post-partum psychosis but anyone seeking advice on the clinical management of this condition will encounter a problem—neither ICD nor the DSM

Climate change is one of the biggest challenges of our time and is likely to affect human beings in substantial ways. Recently, researchers started paying more attention to the changes in climate and their subsequent impact on the social, environmental

The Child Abuse Prevention and Treatment Act (CAPTA), the foundational child-protection legislation in the United States, has been revised more than 20 times since its original passage in 1974. For nearly 30 years, CAPTA didn’t cover infants who had been

If the 1990s were the decade of Peter Kramer’s Listening to Prozac, the 2020s are shaping up to be the decade of Kate Pickett and Richard Wilkinson’s The Inner Level. The popularity of both books beyond the usual academic and

Wealthy nations must do much more, much faster. The United Nations General Assembly in September 2021 will bring countries together at a critical time for marshalling collective action to tackle the global environmental crisis. They will meet again at the

Autism spectrum disorder, a common neurodevelopmental disorder with onset in infancy, is characterized by deficits in social functioning and by repetitive–restrictive behaviors, such as repeated body movements, circumscribed interests, or resistance to change in routines. Pharmacologic…

Individuals with substance use disorders (SUDs) are at increased risk for COVID-19 infection and for adverse outcomes of the infection. Though vaccines are highly effective against COVID-19, their effectiveness in individuals with SUDs might be curtailed by compromised immune status

Happiness was articulated as a fundamental right by the founding fathers of the United States. Few illnesses interfere with the pursuit of happiness more than depression, and approximately 6% of the world’s population is depressed at any given time. Depression

Background Many studies have demonstrated the effectiveness of Screening, Brief Intervention and Referral to Treatment (SBIRT) in addressing substance use problem. However, owing to the shortage of counsellors, it has not been widely used in China. With the development of

Like all sporting events during COVID-19, the 2021 summer Olympics brought a number of firsts, both positive and negative. These included the remarkable spectacle of athletes competing without the usual crowds of spectators, owing to a spike in cases in

Presentation of Case. Dr. Reuben A. Hendler (Psychiatry): A 37-year-old woman was admitted to this hospital because of fever, shortness of breath, and suicidal ideation in March 2020, during the pandemic of coronavirus disease 2019 (Covid-19). Ten days before this

World Psychiatry, Volume 20, Issue 3, Page 437-438, October 2021.

Catatonia, originally conceptualised by Kahlbaum in 1868, is a neuropsychiatric condition that has been found to occur concomitantly with several organic and psychiatric conditions. Starting from the era of Kraepelin and Bleuler, this condition was faultily linked with schizophrenia alone;

Emergency room psychiatry does not often make it into the pages of medical journals. Academic thought—and research money—is mostly directed towards longer-term issues in mental health. Epidemiological studies might track patients over decades. Trial endpoints are often set at weeks,

On April 6, 2021, the Arkansas state legislature overrode a veto by the governor to pass legislation making it illegal for medical professionals to provide gender-affirming treatment to patients with gender dysphoria who are younger than 18 or to refer

Depression is a major source of impairment and suffering in adolescence and is considered to be an important remediable risk factor for suicide, the second leading cause of death among adolescents in the United States. Depression in adolescence predicts depression

When I became a physician, I was not expecting to learn so much about ankle monitors. Over the past few years, I have worked in clinics caring for patients with mental disorders, substance use disorders, or both, many of whom

The most common causes of dementia — Alzheimer’s disease, dementia with Lewy bodies, Parkinson’s disease dementia, vascular dementia, and frontotemporal dementia — may be associated with hallucinations and delusions. This syndrome of dementia-related psychosis causes behavioral disturbances,…

Who is psychiatry for? The prevalence of mental disorders worldwide would suggest that it is a specialty relevant to everyone. But this is not always reflected in the data. For example, when Mikkel Højlund and colleagues looked for evidence comparing

Dementia occurs in a range of progressive neurodegenerative brain disorders, including Alzheimer’s disease, dementia with Lewy bodies, Parkinson’s disease dementia, vascular dementia, and frontotemporal dementia, each classified according to their respective neuropathological characteristics.…

When we took the editorship of Evidence-Based Mental Health (EBMH) at the end of 2013, we set two main objectives: to promote and embed an evidence-based medicine (EBM) approach into daily mental health clinical practice, and to get an impact

Anarthria is the loss of the ability to articulate speech. It can result from a variety of conditions, including stroke and amyotrophic lateral sclerosis. Patients with anarthria may have intact language skills and cognition, and some are able to produce

Of the many functions delegated to the human nervous system, perhaps none is more essentially human than the ability to express one’s thoughts. For persons with severe speech and motor impairments, restoration of the ability to communicate even simple needs

Anarthria is the loss of the ability to articulate speech. It can result from a variety of conditions, including stroke and amyotrophic lateral sclerosis. Patients with anarthria may have intact language skills and cognition, and some are able to produce

Of the many functions delegated to the human nervous system, perhaps none is more essentially human than the ability to express one’s thoughts. For persons with severe speech and motor impairments, restoration of the ability to communicate even simple needs

Background The incidence of paediatric cancers has increased in recent years; however, with advances in the treatment of paediatric cancer, almost 80% of children and adolescents who receive a diagnosis of cancer become long-term survivors. Given the high stress levels

Presentation of Case. Dr. David P. Bullis (Behavioral Medicine, Newton–Wellesley Hospital, Newton, MA): A 54-year-old man was evaluated by the neuropsychology service of this hospital because of irritability, confusion, and odd behaviors. The patient had been in his usual state

The United States faces a growing maternal health crisis: each year, at least 700 women die from pregnancy-related complications and there are more than 25,000 cases of severe maternal morbidity, such as eclampsia or sepsis. These harms prompted the Department

People with severe mental illness have a substantially reduced life expectancy, from 15–20 years less than those without schizophrenia, bipolar, or major depressive disorders. This grim statistic is, unfortunately, one of the few things that all in the mental health

On Jan 21, 1668, the English civil servant and diarist Samuel Pepys received an urgent message from his cousin, Kate Joyce. “If I would see her husband alive,” Pepys wrote, “I must come presently.” He hurried to his relatives’ house

World Psychiatry, Volume 20, Issue 2, Page 197-198, June 2021.

“You still haven’t figured out why?” my patient asked calmly. He was lucid for the first time in days. “No, but we’ve ruled out many diagnoses.” He sighed deeply and shook his head. “This is a hell of a thing.”

The day I graduated from medical school, I could have prescribed enough fentanyl to kill several people. Many of the patients I saw in the hospital during residency clearly had opioid use disorder (OUD), but I couldn’t treat it. I

Accumulation of amyloid-β (Aβ) peptide in the form of amyloid plaques in the brain is an early event in Alzheimer’s disease that putatively leads to neurodegeneration with cognitive and functional impairment. A role for amyloid plaques in disease progression is

Background The COVID-19 pandemic has placed tremendous pressure on healthcare workers who are at the frontline in the battle against it, causing various forms of psychological distress. Aims To outline the prevalence and dynamic changing features of medical workers’ psychological

In The Doors of Perception, Aldous Huxley described his trial of mescaline as “the most extraordinary and significant experience available to human beings this side of the Beatific Vision.” His exegesis was preceded by the synthesis of the hallucinogen lysergic

Major depressive disorder affects approximately 10% of the general population in the United Kingdom, impairs patients’ lives, and is costly to society. Selective serotonin-reuptake inhibitors are first-line treatments for major depressive disorder; however, these drugs take several weeks to work…

In The Doors of Perception, Aldous Huxley described his trial of mescaline as “the most extraordinary and significant experience available to human beings this side of the Beatific Vision.” His exegesis was preceded by the synthesis of the hallucinogen lysergic

Major depressive disorder affects approximately 10% of the general population in the United Kingdom, impairs patients’ lives, and is costly to society. Selective serotonin-reuptake inhibitors are first-line treatments for major depressive disorder; however, these drugs take several weeks to work…

‘None of us will be safe until everyone is safe. Global access to coronavirus vaccines, tests and treatments for everyone who needs them, anywhere, is the only way out’. This statement by Dr Tedros Adhanom Ghebreyesus, Director-General of the WHO

In The Doors of Perception, Aldous Huxley described his trial of mescaline as “the most extraordinary and significant experience available to human beings this side of the Beatific Vision.” His exegesis was preceded by the synthesis of the hallucinogen lysergic

Medicine is a practice built on trust—from patients and from society in general—and this is especially true for psychiatry, in which trust has been forfeited in the past. Transparency is the foundation stone of trust. In research, this can be

Major depressive disorder affects approximately 10% of the general population in the United Kingdom, impairs patients’ lives, and is costly to society. Selective serotonin-reuptake inhibitors are first-line treatments for major depressive disorder; however, these drugs take several weeks to work…

In The Doors of Perception, Aldous Huxley described his trial of mescaline as “the most extraordinary and significant experience available to human beings this side of the Beatific Vision.” His exegesis was preceded by the synthesis of the hallucinogen lysergic

It is May 2020 in Minneapolis. Covid-19 reached us a few months ago, bringing daily routines to a halt. The few cars on the roads speed by, but the city is hushed. We are still wearing sweaters indoors, biding our

Back when I was applying to medical school, there was a moment when I seriously questioned that decision. I was walking to my undergraduate research lab when I received an email from a physician I was shadowing. It contained feedback

Since March 2020, Asian Americans have experienced an alarming increase in racial discrimination and racially motivated violence. Commentators have attributed this distressing fact to the blame placed on China for causing the Covid-19 pandemic, given that the virus was initially

When it comes to public health in the 21st century, scientific breakthroughs and new technologies are likely to be the easy parts. Pfizer managed to develop, test, and get approval for their COVID-19 vaccine in less than a year; a

“Bobby hasn’t come in yet today,” one of my chief residents told me. “He isn’t picking up his phone or answering his pager. Could you go and check on him?” I was in my final year of my internal medicine

Accumulation of amyloid-β (Aβ) peptide in the form of amyloid plaques in the brain is an early event in Alzheimer’s disease that putatively leads to neurodegeneration with cognitive and functional impairment. A role for amyloid plaques in disease progression is

“Bobby hasn’t come in yet today,” one of my chief residents told me. “He isn’t picking up his phone or answering his pager. Could you go and check on him?” I was in my final year of my internal medicine

Despite calls for greater awareness of high rates of depression and suicide among physicians, estimates suggest that only about 1% of medical students with major depressive disorder disclose it as a disability. Throughout the medical school admissions process, training, and

Background There is an urgent need in clinical practice to measure the stress of parenting. The Caregiver Strain Questionnaire (CGSQ) was found to be useful to measure parenting stress, but it has not been validated among the Chinese population. Aims

Almost 70 years ago, Eysenck1 stirred up the community of psychotherapists by postulating that psychotherapies—at that time predominantly psychoanalytic—are not effective in the treatment of psychological disorders. This led to a massive surge of empirically evaluated psychotherapy research and promoted

World Psychiatry, Volume 20, Issue 1, Page 133-134, February 2021.

Maladaptive daydreaming (MD) is an immersive fantasy activity that leads to distress and socio-occupational dysfunction. MD has many features suggestive of behavioural addiction, but research exploring the phenomenology of this clinical construct is limited. MD has also been purported to

Antipsychotic drugs are associated with adverse events such as extrapyramidal symptoms, sedation, weight gain, metabolic disturbances, and hyperprolactinemia that contribute to poor medication adherence and relapses of psychosis. Moreover, 20 to 33% of patients do not have a response to…

“There is no choice between a description of the illness that would give us its sense and an explanation that would give us its cause, and there are no explanations without understanding.” This insight from Maurice Merleau-Ponty’s Phenomenology of Perception

In addition to the sleep–wake cycle and cognitive functions such as learning and memory, intrinsic clocks determine nearly all circadian cycles in physiology, such as daily variation in blood pressure, heart rate, hormone levels, respiratory and exercise capacity, and coagulation.

Background Patients with major depressive disorder (MDD) may have an abnormal peripheral body temperature rhythm, but its relationship with suicidal risk and the response to treatment with antidepressants remain unknown. Aims This study aimed to investigate the feature of peripheral

I still remember my first medical school lectures on endocarditis. Its pernicious nature and protean manifestations seemed to demand the type of careful thought and clinical acumen to which I aspired. It seemed of special importance that it was William

Short-term memory decline is the typical clinical manifestation of Alzheimer’s disease (AD). However, early-onset AD usually has atypical symptoms and may get misdiagnosed. In the present case study, we reported a patient who experienced symptoms of memory loss with progressive

While the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the nervous system remain unclear, there is no doubt that the COVID-19 pandemic is bad for mental health. To alleviate the impact of both the virus and the

There has been a rise in methamphetamine use disorder in the United States, particularly in the Midwest and West, where methamphetamine is a leading cause of overdose deaths. There is no medication approved by the Food and Drug Administration for

Viral encephalitis is a common clinical condition. Its clinical manifestations are variable and include neurological symptoms and psychiatric abnormalities, which makes clinical diagnosis and treatment difficult. To date, there are only a few reported cases on mental symptoms of chronic

World Psychiatry, Volume 20, Issue 1, Page 133-134, February 2021.

The latest in a long series of legal challenges to actions taken by Purdue Pharma to increase prescriptions of its opioid medications has come to an end in the United States. Over the objections of numerous members of Congress, state

Presentation of Case. Dr. David L. Perez: A 62-year-old, left-handed man was seen in the memory disorders clinic of this hospital because of memory loss, personality changes, and odd behavior. Approximately 5 years before this evaluation, the patient’s wife noticed

The COVID-19 has emerged as a public health emergency across the globe. Countries all over the world have been forced to enforce nationwide lockdowns to curb the transmission of this illness, affecting millions of people. The disorder and the lockdowns

7 years ago, as we prepared to launch The Lancet Psychiatry, we had the agreeable task of selecting our Editorial Advisory Board. We wanted people with expertise in different disorders and different types of research, such as epidemiology, neuroimaging, and

The email message’s first words — “Daniel Prude. Say his Name.” — seemed to tell me all I needed to know. Then, my heart racing, I learned that Prude was murdered in my city, where he’d been admitted to my

On June 15, 2020, the U.S. Supreme Court advanced the rights of lesbian, gay, bisexual, transgender, and queer (LGBTQ) Americans by issuing a decision in Bostock v. Clayton County confirming that the prohibition on sex discrimination in employment in Title

Mr. A. a 45-year-old man with a history of benzodiazepine use disorder, was brought to the hospital after having a grand mal seizure while awaiting trial in the holding cell of a municipal courthouse. After being arrested 3 days earlier,

On June 15, 2020, the U.S. Supreme Court advanced the rights of lesbian, gay, bisexual, transgender, and queer (LGBTQ) Americans by issuing a decision in Bostock v. Clayton County confirming that the prohibition on sex discrimination in employment in Title

Mr. A. a 45-year-old man with a history of benzodiazepine use disorder, was brought to the hospital after having a grand mal seizure while awaiting trial in the holding cell of a municipal courthouse. After being arrested 3 days earlier,

On June 15, 2020, the U.S. Supreme Court advanced the rights of lesbian, gay, bisexual, transgender, and queer (LGBTQ) Americans by issuing a decision in Bostock v. Clayton County confirming that the prohibition on sex discrimination in employment in Title

Mr. A. a 45-year-old man with a history of benzodiazepine use disorder, was brought to the hospital after having a grand mal seizure while awaiting trial in the holding cell of a municipal courthouse. After being arrested 3 days earlier,

“Shame, guilt, it kept me awake at night”; “Like being deeply wounded”; “I feel it’s something I’ll have to carry forever”. The kind of statements that a psychiatrist will hear many times during the course of their career in mental

On June 15, 2020, the U.S. Supreme Court advanced the rights of lesbian, gay, bisexual, transgender, and queer (LGBTQ) Americans by issuing a decision in Bostock v. Clayton County confirming that the prohibition on sex discrimination in employment in Title

“Black people love their children with a kind of obsession. You are all we have, and you come to us endangered.” So writes Ta-Nehisi Coates in Between the World and Me, and for all my clinical training, it’s narratives such

World Psychiatry, EarlyView.

Members of the U.S. military are at risk for a range of combat-related injuries and hazardous exposures. Although each theater of operations poses its own risks, over the past 50 years, knowledge of measures for reducing the risks associated with

The transpopulation represents a vulnerable population segment both socially and medically, with a higher incidence of mental health issues. During the COVID-19 outbreak, transgender persons have faced additional social, psychological and physical difficulties.1 2 In Italy and in several other

I couldn’t get out of bed after reading the headline about the murder of George Floyd by a Minneapolis police officer. I lay there in silent horror, staring at the ceiling, utterly numb. I couldn’t unleash the scream of pain

In June 2019, The Mental Health for US campaign launched with the goal of putting mental health policies at the forefront of US politics, and making public discussion of mental illness more informed and less stigmatising. Unfortunately, this effort has

Concerns have been expressed that persons with a pre‐existing mental disorder may represent a population at increased risk for COVID‐19 infection and with a higher likelihood of adverse outcomes of the infection, but there is no systematic research evidence in

Suicide is a public health crisis. Self-harm was the 10th leading cause of death in the United States in 2018, claiming tens of thousands of lives. No single policy can be expected to eliminate a problem of this magnitude. In

In recent years, evolutionary life history theory has been used as a heuristic framework to understand mental health. This article reviews the life history theory and its integration with mental disorders and then introduces representative research methods and related empirical

We report a case of a 39-year-old woman with a psychiatric history of schizoaffective disorder with catatonia, dependent personality disorder and substance use disorder whose symptoms have been very difficult to control. During her most recent inpatient admission, she was

World Psychiatry, Volume 19, Issue 3, Page 307-308, October 2020.

Evolving guidelines for standards of care from the American Diabetes Association and the European Association for the Study of Diabetes recommend treatment escalation when individualized glycemic targets are not reached in patients with type 2 diabetes. Despite these recommendations, clinical…

World Psychiatry, Volume 19, Issue 3, Page 410-411, October 2020.

Attention deficit–hyperactivity disorder (ADHD) is characterized by hyperactivity and impulsivity, by inattention, or by a combination of hyperactivity, impulsivity, and inattention that is inconsistent with developmental level and impairs daily function. The disorder is commonly diagnosed in…

World Psychiatry, Volume 19, Issue 3, Page 307-308, October 2020.

World Psychiatry, Volume 19, Issue 3, Page 410-411, October 2020.

July, 2020, marked the 48th anniversary of the Body Mass Index (BMI), the omnipresent measurement in obesity research, still used by WHO as the standard for obesity statistics. Despite its limitations, the BMI is a stalwart tool owing to its

Presentation of Case. Dr. Rachel A. Meyen (Psychiatry): A 64-year-old Haitian-American man was evaluated at the geriatric psychiatry clinic of this hospital for chronic depression, intrusive thoughts, and fear of being poisoned. During the evaluation, the patient described his mood

Attention deficit–hyperactivity disorder (ADHD) is characterized by hyperactivity and impulsivity, by inattention, or by a combination of hyperactivity, impulsivity, and inattention that is inconsistent with developmental level and impairs daily function. The disorder is commonly diagnosed in…

Presentation of Case. Dr. Rachel A. Meyen (Psychiatry): A 64-year-old Haitian-American man was evaluated at the geriatric psychiatry clinic of this hospital for chronic depression, intrusive thoughts, and fear of being poisoned. During the evaluation, the patient described his mood

West syndrome (WS) is the most common epileptic syndrome in infancy characterised by epileptic spasms, hypsarrhythmia and neurodevelopmental problems. Epileptic spasms remain in many ways a conundrum, and the ideal intervention, as well as how to screen patients to provide

Background Erectile dysfunction (ED) has gradually become an important issue that seriously affects the quality of life of Chinese men. In addition to classic oral medications, psychotherapeutic interventions are increasingly being used in the treatment of ED. Aim This study

The Lancet Psychiatry’s recent Position Paper on how mental health care should change as a consequence of the COVID-19 pandemic was welcomed by many, but others expressed disquiet at its lack of authors from low-income and middle-income countries. “Far too

Presentation of Case. Dr. Meridale V. Baggett (Medicine): A 60-year-old woman presented to this hospital with altered mental status during the pandemic of coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The patient

Background The elderly population in India is expected to grow enormously by 2050 owing to an increase in life expectancy. Community-based data on the prevalence of psychological morbidity, abuse and cognitive dysfunction are scarce. Aims To determine the prevalence of

The development of highly curative direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection has transformed clinical management of HCV and provided the impetus for the World Health Organization’s ambitious HCV-related targets for 2030. These targets include marked improvements

Uncertain prognoses, looming severe shortages of resources for testing and treatment and for protecting responders and health care providers from infection, imposition of unfamiliar public health measures that infringe on personal freedoms, large and growing financial losses, and conflicting…

Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning with the reader (regular type). The authors’ commentary follows.

Uncertain prognoses, looming severe shortages of resources for testing and treatment and for protecting responders and health care providers from infection, imposition of unfamiliar public health measures that infringe on personal freedoms, large and growing financial losses, and conflicting…

On June 15, 2020, the U.S. Supreme Court advanced the rights of lesbian, gay, bisexual, transgender, and queer (LGBTQ) Americans by issuing a decision in Bostock v. Clayton County confirming that the prohibition on sex discrimination in employment in Title

Background With the rapid increase in ageing population, China is confronted with the daunting challenge of a growing number of patients with neurocognitive disorders (NCDs). This trend makes the maintenance of self-health and early intervention essential, highlighting the need for

Psychiatric disorders are by their nature multifaceted, as they reflect the complexity of both the human brain and the human condition. What are classified as symptoms of a disorder result from biological susceptibility or resilience interacting with features of the

COVID-19 has evolved rapidly into a pandemic with global impacts. However, as the pandemic has developed, it has become increasingly evident that the risks of COVID-19, both in terms of infection rates and particularly of severe complications, are not equal

To rapidly communicate short reports of innovative responses to Covid-19 around the world, along with a range of current thinking on policy and strategy relevant to the pandemic, the Journal has initiated the Covid-19 Notes series. One April morning during

Background The prevalence of Alzheimer’s disease (AD) comorbid with depression is common. However, the mechanisms of AD with depression remain unclear. Aims To investigate the regional alterations of brain activity of AD with depression in resting-state functional magnetic resonance imaging

To the Editor: Nearly 70,000 people in the United States die each year from a drug overdose. Opioid-involved overdose deaths may be preventable by the timely administration of naloxone. Eleven countries have responded to health concerns regarding people who use

Mood fluctuations are common during normal daily life as a result of either stressful or pleasant events. However, severe and persistent mood swings that result in psychological distress and behavioral impairment may be symptomatic of an underlying affective disorder. Affective

“Try Googling ‘record-setting lake trout New Hampshire,’” I found myself saying recently to an anxious patient while we explored ways to cope with the Covid-19 pandemic. He loves fishing, and I remembered a story in the paper recently — just

I couldn’t get out of bed after reading the headline about the murder of George Floyd by a Minneapolis police officer. I lay there in silent horror, staring at the ceiling, utterly numb. I couldn’t unleash the scream of pain

Presentation of Case. Dr. Rachel M. Erdil (Medicine and Pediatrics): A 7-year-old girl who had immigrated to the United States from Central America was evaluated in the asylum clinic of this hospital — where forensic medical evaluations of asylum seekers

Suicide attempts are often impulsive acts, driven by transient life crises. Most attempts are not fatal, and most people who attempt suicide do not go on to die in a future suicide. Whether a suicide attempt is fatal depends heavily

In early April, 2008, as the USA was in the midst of its worst economic crisis since the great depression, then presidential candidate Barack Obama described people in rural, small US towns as responding to tough economic times by “clinging

In March 2020, as the coronavirus pandemic spread throughout the United States, Americans bought nearly 2 million guns — the second highest monthly total in the decades since such records have been kept. Previous spikes in U.S. firearm sales have

Background Consultation liaison psychiatry (CLP) as a subspecialty is defined as the area of clinical psychiatry that encompasses clinical understanding, teaching and research activities of psychiatrists and allied health professionals in the non-psychiatric divisions of a general hospital. Psychiatric comorbidity