Objective Little is known about intestinal anastomotic leakage and stenosis in young children (≤3 years of age). The purpose of this study is to answer the following questions: (1) what is the incidence of anastomotic stenosis and leakage in infants?
Survey on surgical treatment of neonatal necrotizing enterocolitis in China 2022
Objective The aim of this study was to identify the state of surgical treatment of neonatal necrotizing enterocolitis (NEC) in China. Methods A total of 246 delegates (88.0% senior surgeons) completed a survey sent by the Neonatal Surgery Group of
Role and significance of SIRT1 in regulating the LPS-activated pyroptosis pathway in children with congenital hydronephrosis
Objective To explore the characteristics and mechanism of sirtuin 1 (SIRT1) in lipopolysaccharide (LPS)-activated pyroptosis in the renal tissue of children with congenital hydronephrosis (CHn). Methods We detected the expression characteristics and clinical significance of SIRT1 and pyroptosis pathway proteins
Dual ultrasound-guided totally implantable venous access ports via the right internal jugular vein in pediatric patients with cancer: a preliminary experience in a single institution
Objective To assess the efficacy and safety of dual ultrasound-guided (DUG) totally implantable venous access port (TIVAP) implantation (namely, using ultrasound-guided percutaneous puncture with transesophageal echocardiography-guided catheterization) via the right internal jugular vein (IJV) in pediatric patients with cancer. Methods
Patterns, procedures, and indications for pediatric surgery in a Tanzanian Refugee Camp: a 20-year experience
Background There are 103 million displaced people worldwide, 41% of whom are children. Data on the provision of surgery in humanitarian settings are limited. Even scarcer is literature on pediatric surgery performed in humanitarian settings, particularly protracted humanitarian settings. Methods
Radiomic-based machine learning model for predicting the surgical risk in children with abdominal neuroblastoma
Background Preoperative imaging assessment of surgical risk is very important for the prognosis of these children. To develop and validate a radiomics-based machine learning model based on the analysis of radiomics features to predict surgical risk in children with abdominal
Congenital diaphragmatic hernia survival in an English regional ECMO center
Introduction Congenital diaphragmatic hernia (CDH) remains a cause of neonatal death. Our aims are to describe contemporary rates of survival and the variables associated with this outcome, contrasting these with our study of two decades earlier and recent reports. Materials
Effectiveness of psychosocial interventions for pediatric patients with scoliosis: a systematic review
Background Pediatric patients affected by scoliosis have complex psychological and social care needs, and may benefit from psychosocial interventions. We therefore aimed to summarize evidence of the efficacy of psychosocial interventions for this patient population. Methods Literature was identified by
Tribute to reviewers (January 1, 2022 to December 31, 2022)
Analysis and comparison of failure causes of minimally invasive surgical closure of ventricular septal defects in children
Objectives The aims of the present study were to explore the causes of minimally invasive surgical ventricular septal defect (VSD) closure failure under transesophageal echocardiography guidance and thus to improve the success rate of surgical VSD closure. Methods From January
Epidemiological characteristics of live births with esophageal atresia in Sao Paulo State, Brazil, from 2005 to 2018
Background The estimated prevalence of esophageal atresia (EA) is 1 in 2500–4500 live births (LBs). Researchers have already identified risk factors, but the mechanisms are still unknown. The aim of this study is to identify EA prevalence trends and its
The etiological spectrum of bowel obstruction and early postoperative outcome among neonates at a tertiary hospital in Uganda
Background Bowel obstruction is a common surgical emergency in newborns. One-fourth of neonates with obstruction suffer postoperative complications, with high mortality, especially in low-income countries. Factors attributed to mortality include prematurity, late presentation and associated multiple congenital anomalies. The prevalence
Neonatal pneumothorax in congenital diaphragmatic hernia: Be wary of high ventilatory pressures
Background Patients with congenital diaphragmatic hernia (CDH) require invasive respiratory support and higher ventilator pressures may be associated with barotrauma. We sought to evaluate the risk factors associated with pneumothorax in CDH neonates prior to repair. Methods We retrospectively reviewed
Outcomes of biliary atresia splenic malformation (BASM) syndrome following Kasai operation: a systematic review and meta-analysis
Tribute to reviewers
Pediatric dog bite injuries in the USA: a systematic review
Introduction Dog bites are one of the leading causes of non-fatal emergency room visits in children. These injuries not only cause physical harm but can lead to long-term psychological stress. This study evaluated the current literature related to pediatric dog
Hypospadias in toddlers: a multivariable study of prognostic factors in distal to mid-shaft hypospadias and review of literature
Background Tubularized incised plate urethroplasty is the most common hypospadias repair technique. However, there are unanswered questions and debates about the anatomical prognostic factors affecting the repair outcomes. This study tried to address some of the problems in the studies
Child access prevention legislative language and pediatric firearm injury rates
Backgroud Firearm injuries are a significant public health problem facing young people in the USA. In 2015, a total of 16 878 people under 19 years old were injured or killed by firearms. To reduce firearm injuries, 29 states and
Association of anesthetic and surgical risk factors with outcomes of initial diagnostic biopsies in a current cohort of children with anterior mediastinal masses
Background Diagnostic biopsies of pediatric anterior mediastinal masses (AMMs) are high-risk procedures in which general anesthesia (GA) is traditionally avoided. However, awareness of historically recognized risk factors and corresponding perioperative management have improved over time and may now no longer
Child access prevention legislative language and pediatric firearm injury rates
Backgroud Firearm injuries are a significant public health problem facing young people in the USA. In 2015, a total of 16 878 people under 19 years old were injured or killed by firearms. To reduce firearm injuries, 29 states and
Diagnostic value of 3D-FLAIR MRI in children with sudden deafness caused by inner ear hemorrhage
Objective To investigate the diagnostic value of three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) MRI in children with sudden deafness caused by inner ear hemorrhage. Methods The diagnostic efficacies of three different MRI sequences in the examination of the inner ear for
Coronal sulcus-based ventral mucosal flap to help penile coverage in severe concealed penis
Introduction There are many techniques to treat congenital concealed penis (CP). Skin resurfacing is the most difficult step in severe cases. We aim to show medium-term results of coronal sulcus–based triangular ventral mucosal flap (CBVMF) as a treatment of prepubertal
Unexpected findings at laparotomy of a 12-year-old girl with obstructive jaundice and choledocholithiasis: a case report
Predictors of poor outcomes in children with tracheoesophageal fistula/oesophageal atresia: an Australian experience
Objective The aim of this study is to characterize long-term morbidities of oesophageal atresia (OA) with or without tracheoesophageal fistula (TOF). Methods Infants born with OA/TOF from 2000 to 2016 in Western Australia were included for analysis. Infants were categorized
Genetic and epigenetic mechanisms in the development of congenital heart diseases
Congenital heart disease (CHD) is the most common of congenital cardiovascular malformations associated with birth defects, and it results in significant morbidity and mortality worldwide. The classification of CHD is still elusive owing to the complex pathogenesis of CHD. Advances
Specific imaging features of intestinal perforation on supine abdominal X-ray evaluation in infants with necrotizing enterocolitis
Background Necrotizing enterocolitis (NEC) is associated with high mortality and morbidity in neonates. For infants with NEC, intestinal perforation is the most serious complication, and confirming perforation and performing radical surgical treatment as early as possible may reduce mortality and
Severe liver trauma among pediatric patients in the Japan Trauma Registry
Background Limited information exists regarding the clinical characteristics, management practices, and outcomes of pediatric patients with liver injury in Japan. The aim of this study is to evaluate the characteristics, management, and outcome of pediatric patients with liver injury in
Tribute to reviewers
Study of risk factors for intraoperative hypothermia during pediatric burn surgery
Background Intraoperative hypothermia (core temperature <36.0°C) is common during the perioperative period and can result in adverse consequences, especially in children. We aimed to determine the incidence of intraoperative hypothermia and its risk factors in pediatric patients during burn surgery.
Hydrostatic reduction of intussusception with intermittent radiography: an alternative to fluoroscopy or ultrasound-guided reduction in low-income and middle-income countries
Background Although hydrostatic reduction of intussusception with ultrasound (US) or fluoroscopy guidance is well known, it is not yet well established in many low-income and middle-income countries. The aim of the study is to report our results of hydrostatic reduction
Acute pancreatitis revealing duodenal duplication in a child
Targeting autophagy in neuroblastoma
Background Neuroblastoma (NB) is the most common extracellular solid tumor among children accounting for serious mortality. Macroautophagy, a common housekeeping mechanism to maintain cellular homeostasis in eukaryotic cells, is involved in tumorigenesis and chemoresistance in a spectrum of cancers. Data
Delayed exploration and repair to manage pediatric anterior urethral blast injury
Kidney structure and function in dilating vesicoureteral reflux patients with anorectal malformation
Background We assessed the impact of anorectal malformation (ARM) on the kidneys of children with dilating vesicoureteral reflux (D-VUR) ≥grade III using a simple dimercaptosuccinic acid (DMSA) scintigraphy scan based renal dysfunction score (RDS). Methods The medical records of 121
Early prediction of acute kidney injury in neonates with cardiac surgery
Background Acute kidney injury (AKI) occurs in 42%–64% of the neonatal patients experiencing cardiac surgery, contributing to postoperative morbidity and mortality. Current diagnostic criteria, which are mainly based on serum creatinine and hourly urine output, are not sufficiently sensitive and
Failed ventriculoperitoneal shunt as treatment of infantile hydrocephalus
Do we control gastric residuals unnecessarily in premature newborns? AGRA study: avoidance of gastric residual aspiration
Aspiration and evaluation of gastric residuals are commonly performed interventions before each feeding in intensive care units, especially in very low birthweight infants. However, there is no sufficient evidence about the necessity of routine gastric residual aspiration. In this study,
Neonatal neuroimaging after repair of congenital diaphragmatic hernia and long-term neurodevelopmental outcome
Objective Previous outcome reports of congenital diaphragmatic hernia (CDH) have described neuroimaging anomalies and neurodevelopmental impairment. However, the link between imaging and outcome has not been described. We aimed to determine whether routine postoperative neonatal neuroimaging in infants with CDH
Validation and modification of the ‘Chiang Mai University Intussusception scoring system used to predict failure of non-surgical treatment in infantile intussusception
Background This study aimed to validate and modify the recently released Chiang Mai University Intussusception (CMUI) scoring system in predicting failure of non-surgical management of infantile intussusception. Methods A retrospective review was conducted in 151 cases of infantile intussusception who
Analysis of the risk of ovarian torsion in 49 consecutive pediatric patients treated at a single institution
Purpose An early diagnosis of ovarian torsion is sometimes difficult due to variable clinical symptoms and non-specific imaging findings. We retrospectively reviewed patients with pediatric ovarian masses manifesting torsion. Methods Fifty-eight ovarian masses (55 episodes) in 49 non-neonatal patients treated
Screw osteosynthesis of transverse fracture of the patella in children
Objective Patella fractures in children are rare, with an incidence of less than 1% of all pediatric fractures. Literature describes different surgical techniques and outcomes, but there is not a specified superior technique for children. The aim of this study
Validity of Alvarado Score in predicting disease severity and postoperative complication in pediatric acute appendicitis
Background This study evaluates the validity of Alvarado Score in predicting disease severity and the development of postoperative complications in pediatric appendicitis. Methods This is a retrospective, bicentered study on pediatric patients with emergency appendicectomy performed from 2006 to 2016.