Göz Hastalıkları

Altered retinoid metabolism gene expression in chronic Stevens-Johnson’s syndrome (see page 1015) Altered vitamin A metabolism in chronic ocular sequelae of SJS. Photophobia and sensations of dryness in migraine patients occur independent of baseline tear volume and improve following botulinum

Prevalence and causes of vision loss in North Africa and Middle East in 2015: Magnitude, temporal trends, and projections (see page 863) The age-standardised prevalence of vision impairment for all ages and genders decreased from 1990 to 2015 in NAME.

Objective To determine the common indications for, and outcomes of pars plana vitrectomy surgery among black Africans in a low-resource setting. Methods and Analysis A retrospective, non-comparative case review was undertaken. Data from 1000 consecutive eyes of 1000 patients in

Astigmatism and its components in 12-year-old Chinese children: the Anyang Childhood Eye Study (see page 768) In Chinese children (mostly 12-year-olds) with high a prevalence of astigmatism, refractive (RA) and corneal (CA) astigmatism were mainly “with-the-rule” and increased with the

Prior non-irradiative focal therapies do not compromise the efficacy of delayed episcleral plaque brachytherapy in retinoblastoma (see page 699) In a retrospective study of 50 patients, the lack of prior diode or green laser therapy was predictive of an increased

Background/aims To monitor treatment-naïve patients with wet age-related macular degeneration (wet AMD) receiving intravitreal aflibercept (IVT-AFL) in France. Methods RAINBOW (Real life use of intravitreal Aflibercept In FraNce – oBservatiOnal study in Wet age-related macular degeneration) is an ongoing, observational,

Choriocapillaris and retinal vascular plexus density of diabetic eyes using Split-spectrum Amplitude-Decorrelation spectral domain optical coherence tomography angiography (see page 452) Capillary perfusion density in Choriocapillaris and retinal vascular plexuses in diabetic patients were observed in association with worsening retinopathy

Objective Explore relationships between systemic exposure to intravitreal aflibercept injection (IAI) and systemic pharmacodynamic effects via post hoc analyses of clinical trials of IAI for neovascular age-related macular degeneration (nAMD) or diabetic macular oedema (DME). Methods and analysis Adults from

In vivo confocal microscopy indicates an inverse relationship between the subbasal corneal plexus and the conjunctivalization in patients with limbal stem cell deficiency (see page 327) In this study the authors observed an inverse relationsip between sub-basal corneal nerve plexus

Micro-interventional endocapsular nucleus disassembly: novel technique and results of first-in-human randomized controlled study (see page 176) In a prospective, masked, multi-surgeon randomised clinical trail, the authors observed that microinterventional cataract fragmentation and endocapsular nucleus disassembly prior to conventional phacoemulsification safely

Background/Aims Optical coherence tomography (OCT) has become standard of care in the diagnosis and management of a myriad of retinal and optic nerve pathology. Access to diagnostic equipment and skilled imaging personnel in the after-hours setting is often limited. We

Neuroretinal atrophy following resolution of macular oedema in retinal vein occlusion (see page 36) In this study of patients with retinal vein occlusion treated with ranibizumab, significant neuroretinal thinning was observed after the resolution of macular oedema in 11% of

Acanthamoeba keratitis: confirmation of the UK outbreak and a prospective case–control study identifying contributing risk factors (see page 1621) There has been a threefold increase in Acanthamoeba keratitis among contact lens users in South East England since 2010–2011. Risk factors

Background/aims Teleophthalmology is well positioned to play a key role in screening of major chronic eye diseases. Economic evaluation of cost-effectiveness of teleophthalmology, however, is lacking. This study provides a systematic review of economic studies of teleophthalmology screening for diabetic

Epiblepharon, a common occurrence among children of East Asian descent, is a congenital anomaly whereby a horizontal skin fold across the eyelid (upper or lower) overlaps the eyelid margin resulting in inturning of the eyelashes.1–3 This usually occurs in the

Aim To evaluate glaucoma-associated mortality in a rural cohort in India. Methods The study cohort comprised individuals aged 40 years and above who took part in the Andhra Pradesh Eye Disease Study (APEDS1) during 1996–2000. All participants underwent detailed comprehensive

Background/aims To determine the diagnostic accuracy of trained rural ophthalmologists and non-medical image graders in the assessment of diabetic retinopathy (DR) in rural China. Methods Consecutive patients with diabetes mellitus were examined from January 2014 to December 2015 at 10

Non-incisional eyelid everting suture technique for treating lower lid epiblepharon (see page 1504) Non-incisional eyelid everting sutures can be useful in patients with mild to moderate lower lid epiblepharon and it is important to determine the appropriate indications for this

Objective To evaluate the success of an intravitreal injection of ocriplasmin to release symptomatic vitreomacular traction (VMT) and close a full-thickness macular hole. Methods and analysis An observational retrospective multicentre study conducted in Italy. Patients with symptomatic distortion and loss

Objective We investigated the efficacy of additional topical betamethasone in persistent cystoid macular oedema (CMO) after carbonic anhydrase inhibitors (CAIs) therapy. Methods and analysis This retrospective cohort study included 16 eyes of 10 patients with retinitis pigmentosa (RP). All patients

Objective Microbial infection has been reported to cause blepharitis, conjunctivitis and keratitis. We evaluated the safety and efficacy of a foam formulation of 2% 4-terpineol (T4O) against common ocular microorganisms. Material and methods The antimicrobial effect of a 2% T4O

Background/aims To report alterations in visual acuity and visual pathway structure over an interval of 1–3 years in a cohort of children, adolescents and young adults who have Wolfram syndrome (WFS) and to describe the range of disease severity evident

Objective To determine the prevalence of, associations with and diagnoses leading to mild visual impairment or worse (logMAR >0.3) in middle-aged adults in the UK Biobank study. Methods and analysis Prevalence estimates for monocular and binocular visual impairment were determined

Background Trachoma is the leading infectious cause of blindness. Until recently, reliable data on the global extent of the disease, detailed plans for elimination, and government, donor and partner engagement were all inadequate. Methods The trachoma community undertook a systematic, three-pronged strategy

Purpose To determine the prevalence of refractive errors in Colombia and its relations with demographic and socioeconomic variables. Methods A cross-sectional study performed in 10 Colombian administrative districts (MIOPUR study), including children and adolescents from 8 to 17 years old

Polytetrafluoroethylene (Gore-Tex) suture is preferred for scleral fixation of intraocular lenses or capsular tension devices as it is more resilient to breakage than polypropylene 10–0. However, manipulation of the thick calibre and overcurved configuration of the Gore-Tex needle within the eye

The BJO is primarily a clinical and scientific journal and rarely comments on commercial activities. Nevertheless, the recent developments in the field of glaucoma surgery,1 merit some comment. An area that has traditionally failed to attract significant commercial interest has

Effect of intravitreal triamcinolone acetonide injection at the end of vitrectomy for vitreous hemorrhage related to proliferative diabetic retinopathy (see page 1351) In a prospective multicenter randomised study, intravitreal injection of triamcinolone acetonide at the end of vitrectomy was associated