Incremental predictive value of left atrial strain and left atrial appendage function in rhythm outcome of non-valvular atrial fibrillation patients after catheter ablation

Objective The purpose of this study was to develop a non-invasive and convenient nomogram based on speckle tracking echocardiography, left atrial appendage function and clinical factors to predict the risk of atrial fibrillation (AF) recurrence after catheter ablation. Methods A

Sugar-coated RNAs

Nature Reviews Genetics, Published online: 24 June 2021; doi:10.1038/s41576-021-00388-y A study in Cell describes the discovery of a conserved set of small non-coding RNAs that are glycosylated in diverse cell types. These glycoRNAs are found at the surface of cells,

Society for Maternal-Fetal Medicine (SMFM) Consult Series #57: Evaluation and Management of Isolated Soft Ultrasound Markers for Aneuploidy in the Second Trimester

Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have greatly evolved over the last 2 decades, the relative importance

Subgroups of failure after surgery for pelvic organ prolapse and associations with quality of life outcomes: a longitudinal cluster analysis

Treatment outcomes after pelvic organ prolapse (POP) surgery are often presented as dichotomous ‘success or failure’ based upon anatomic and symptom criteria. However, clinical experience suggests some women with outcome ‘failures’ are asymptomatic and perceive their surgery to be successful,

Anti-Müllerian hormone levels among contraceptive users: evidence from a cross-sectional cohort of 27,125 individuals

Anti-Müllerian Hormone has become the clinical biomarker-based standard to assess ovarian reserve. As anti-Müllerian hormone testing becomes more common, more individuals are seeking to interpret values obtained while using contraceptives. To appropriately counsel women, a better understanding of anti-Müllerian hormone

Orbital Cowpox

A 28-year-old woman presented to the emergency department with a 5-day history of worsening redness, irritation, and discharge in the right eye. Examination of the eye showed periocular swelling, conjunctival injection, and chemosis as well as purulent discharge. She received

Merging Mortalities

I recently recalled a patient who was admitted to the hospital during my first medical school rotation in the late 1970s. He was a 25-year-old man with Hodgkin’s lymphoma. Typically, medical students on call would eagerly divide up the newly

Hypertensive Heartbreak

Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning with the reader (regular type). The authors’ commentary follows.

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